Nirogi Knowledge Library

Curated health research from the world's top 50 medical institutions. The science behind every Nirogi AI recommendation.

40 articles

Harvard Medical School2023Heart Health

Effect of physical activity on cardiovascular mortality

Large cohort evidence that regular moderate activity lowers cardiovascular death risk. Benefits begin well below the 150-minute weekly target.

Used by: HeartSense

Open source
ICMR2024Diabetes

Dietary patterns and Type 2 Diabetes risk in India

India-specific analysis of refined-carbohydrate heavy diets and diabetes incidence. Replacing white rice with millets or whole grains reduced risk.

Used by: SugarSense, CalorieEye

Open source
Mayo Clinic2023Cancer

Early detection of lung cancer via low-dose CT screening

Low-dose CT screening in high-risk smokers detects lung cancer at earlier, treatable stages and reduces mortality.

Used by: CancerSense, ScanIQ

Open source
Oxford University2022Sleep

Sleep duration and all-cause mortality meta-analysis

Pooled analysis showing a U-shaped relationship between sleep duration and mortality, with 7-8 hours as the optimum.

Used by: Sleep Tracker

Open source
World Health Organization2020Exercise

WHO guidelines on physical activity and sedentary behaviour

Global recommendations for weekly activity across age groups, including strength training and limiting sedentary time.

Used by: Exercise Tracker

Open source
American Heart Association2021Heart Health

Sodium reduction and blood pressure control

Reducing dietary sodium produces meaningful blood pressure drops, especially in salt-sensitive and hypertensive adults.

Used by: HeartSense, CalorieEye

Open source
BMJ2022Medicines

Paracetamol dosing and hepatotoxicity risk

Review of safe paracetamol dosing thresholds and the liver injury risk from chronic supratherapeutic use.

Used by: MedGuard

Open source
Stanford Medicine2023Gut Health

Gut microbiome diversity and metabolic health

Higher microbiome diversity correlates with better insulin sensitivity and lower inflammatory markers.

Used by: Gut Health

Open source
NIMHANS Bengaluru2022Mental Health

Depression prevalence and treatment gap in India

National survey data on depression prevalence and the large proportion of Indians who never receive treatment.

Used by: Mind & Mood

Open source
Johns Hopkins Medicine2023Vision and Hearing

Blue light exposure and digital eye strain

Prolonged screen use reduces blink rate and causes accommodative fatigue; scheduled breaks are the most effective mitigation.

Used by: Eye Strain

Open source
AIIMS New Delhi2023India Health

Hypertension burden in urban India

Urban Indian adults show rising hypertension prevalence with low awareness and control rates.

Used by: HeartSense

Open source
NEJM2021Nutrition

Intermittent fasting and metabolic outcomes

Time-restricted eating produces modest weight loss largely explained by reduced calorie intake.

Used by: CalorieEye, Diet Plan

Open source
The Lancet India2022India Health

Vitamin D deficiency and bone health in South Asians

High deficiency rates in Indian adults despite abundant sunlight, driven by skin pigmentation and indoor lifestyles.

Used by: Bone Health

Open source
World Health Organization2022Vision and Hearing

Hearing loss from personal audio devices

Unsafe listening levels among young people are a major preventable cause of hearing loss.

Used by: Hearing Health

Open source
Cochrane Reviews2021Exercise

Yoga and blood pressure reduction — systematic review

Meta-analysis of yoga interventions showing small but consistent reductions in blood pressure.

Used by: Exercise Tracker, Breathe

Open source
Cleveland Clinic2023Sleep

Sleep apnoea screening in primary care

Simple questionnaires plus overnight oximetry identify most moderate-to-severe obstructive sleep apnoea cases.

Used by: Sleep Tracker

Open source
ICMR2023India Health

Antibiotic resistance patterns in Indian hospitals

Surveillance data showing rising resistance in common pathogens and the role of over-the-counter antibiotic use.

Used by: MedGuard

Open source
The Lancet2023Cancer

Processed food consumption and cancer risk

Cohort study linking ultra-processed food intake to increased overall cancer incidence.

Used by: CancerSense, CalorieEye

Open source
Massachusetts General Hospital2022Mental Health

Mindfulness-based stress reduction outcomes

Eight-week mindfulness programmes reduce anxiety and perceived stress with durable effects at six months.

Used by: Mind & Mood, Stress

Open source
NIH2021Nutrition

Hydration status and cognitive performance

Mild dehydration measurably reduces attention, short-term memory and mood.

Used by: Water Tracker

Open source
ICMR2022India Health

Anaemia in Indian women — national survey analysis

Persistent high anaemia prevalence among Indian women of reproductive age with dietary iron as a key gap.

Used by: Daily Energy

Open source
JAMA2022Heart Health

Statins for primary prevention — benefit and harm

Weighing cardiovascular risk reduction against side effects in adults without established heart disease.

Used by: HeartSense, MedGuard

Open source
Cambridge University2023Mental Health

Screen time and adolescent mental health

Dose-response relationship between heavy social media use and adolescent depressive symptoms.

Used by: Mind & Mood, Eye Strain

Open source
Harvard Medical School2021Gut Health

Fibre intake and colorectal cancer prevention

Higher dietary fibre intake is associated with meaningfully lower colorectal cancer incidence.

Used by: Gut Health, CancerSense

Open source
AIIMS New Delhi2024India Health

Air pollution and respiratory disease in Indian cities

PM2.5 exposure in major Indian cities is linked to reduced lung function and increased hospital admissions.

Used by: Oxygen, HeartSense

Open source
Imperial College London2022Diabetes

Diabetes remission through weight loss

Structured weight-loss programmes achieved type 2 diabetes remission in a substantial minority of participants.

Used by: SugarSense, Weight

Open source
Mayo Clinic2023Medicines

Thyroid disorders — screening and management

Guidance on when to screen for thyroid dysfunction and how to interpret borderline TSH results.

Used by: MedGuard

Open source
Karolinska Institute2023India Health

Heat stress and kidney injury in outdoor workers

Repeated occupational heat exposure without hydration is linked to chronic kidney disease of unknown origin.

Used by: Temperature, Water Tracker

Open source
Memorial Sloan Kettering2022Cancer

Prostate cancer screening — benefits and overdiagnosis

PSA screening reduces prostate cancer mortality modestly but leads to significant overdiagnosis.

Used by: CancerSense

Open source
Cochrane Reviews2022Gut Health

Probiotics for irritable bowel syndrome

Certain probiotic strains improve IBS symptoms, though effects vary widely between products.

Used by: Gut Health

Open source
European Society of Cardiology2021Heart Health

Cardiac rehabilitation after heart attack

Structured cardiac rehab lowers re-admission and mortality after myocardial infarction.

Used by: Exercise Tracker, HeartSense

Open source
Cleveland Clinic2022Nutrition

Micronutrient deficiencies in vegetarian diets

Practical guidance on B12, iron, zinc and omega-3 for predominantly plant-based Indian diets.

Used by: Diet Plan, CalorieEye

Open source
JAMA2022Mental Health

Physical activity and depression prevention

Even modest activity levels lower the risk of developing depression across age groups.

Used by: Exercise Tracker, Mind & Mood

Open source
American Diabetes Association2023Diabetes

Continuous glucose monitoring in type 2 diabetes

CGM improves time-in-range and HbA1c even in non-insulin-treated type 2 diabetes.

Used by: SugarSense, Glucose

Open source
Brigham and Women's Hospital2021Nutrition

Bone density loss after menopause

Rapid bone loss in early post-menopause and the role of weight-bearing exercise, calcium and vitamin D.

Used by: Bone Health

Open source
Tata Memorial Centre2023Cancer

Tobacco use and oral cancer risk in India

Smokeless tobacco is the dominant driver of India's high oral cancer burden.

Used by: CancerSense

Open source
The Lancet2022Sleep

Sleep, circadian rhythm and shift work

Chronic shift work disrupts circadian alignment and raises metabolic and cardiovascular risk.

Used by: Sleep Tracker, Energy

Open source
UpToDate2023Medicines

Drug interactions in polypharmacy for elderly patients

Older adults on five or more medicines face substantially higher interaction and fall risk.

Used by: MedGuard, Prescription Reader

Open source
Global Burden of Disease (IHME)2023India Health

Global burden of chronic kidney disease

CKD is a rapidly growing cause of death worldwide, with diabetes and hypertension as leading causes.

Used by: MedGuard

Open source
MIT Health Sciences2023Heart Health

Heart rate variability as a stress marker

HRV is a practical non-invasive indicator of autonomic balance and recovery status.

Used by: Stress, Heart Rhythm

Open source